Featured Speakers
Day 1 November 02, 2015 Monday
Terry Richard Stouch, Ph.D, Science for Solutions, LLC, USA
Title: The errors of our ways: Accounting for known unknowns in Drug Discovery research
Harold C. Smith, University of Rochester, USA
Title: Going Beyond Repurposing Cancer Drugs: Identification of Novel HIV Drug Leads that are Broadly Neutralizing of HIV1 Clades and Drug-resistant Strains
Nikolai Zhelev, Ph.D, CBiol, EurProBiol, FIBiol, FMBNAM, FSB, Abertay University, UK
Title: Recent advances and novel approaches in the discovery and development of cyclin-dependent kinase inhibitors as new therapeutics in oncology and cardiology
Alex MacKerell, Ph.D., University of Maryland, USA
Title: Functional Group Affinity Mapping and Rapid Estimation of Relative Ligand Affinities by Site Identification by Ligand Competitive Saturation (SILCS)
Mark Feitelson, Ph.D, Temple University, USA
Title: Preclinical characterization of GLS4: an inhibitor of hepatitis B virus core particle assembly
Jeffrey Kurz, Ph.D, Pfizer, Inc., USA
Title: Radiolabeled methods for ADME of protein therapeutics in preclinical development
Saydiganikhodja I. Ismailov, Ph.D, Uzbekistan Public Health Ministry, Uzbekistan
Title: Combination of strontium ranelate plus alfacalcidol in the treatment of postmenopausal osteoporosis
Alan D Rogol MD, University of Virginia Medical School, USA
Title: Androgen Therapy in Adolescents
Om Dhingra, SOV Therapeutics, Inc., USA
Title: Challenges in the development of an oral tstosterone replacement therapy for adoloscent and adult hypogonadism treatment
Pablo Sobrado, Ph.D Virginia Tech, USA
Title: Inhibition of siderophore biosynthesis in fungi and bacteria
Sangkil Lee, Ph.D Keimyung University, South Korea
Title: Iontophoretic buccal drug delivery: Can it be a breakthrough strategy to promote the therapeutic effects of biopharmaceuticals?
Jun Fang, Ph.D, Sojo University, Japan
Title: Photodynamic therapy and imaging based on tumor-targeted nanoprobe, pHPMA-conjugated zinc protoporphyrin, and its augmentation
Takashi Tsukamoto, Ph.D Johns Hopkins University, USA
Title: D-amino acid oxidase inhibitors as pharmaco-enhancers of D-serine
Mukhtar Dauda, MD, Bayero University, Nigeria
Title: Current trend in the sensitivity of Plasmodium falciparum to Coartemisinin therapy
in northern Nigeria as at 2015
Rosanna Filosa, University of Naples, Italy
Title: Synthesis, structure-activity relationship, and biological evaluation of novel benzoquinones as potent inhibitors of 5-lipoxygenase
Young Researchers
Wenjun Zhang, Northeastern University, USA
Title: Noninvasive salivary glucose monitoring using On-chip Nano-biosensor
Selene Collarile, University of Naples, Italy
Title: Structure–Activity relationship study of Arbidol derivatives as inhibitors of chikungunya virus replication
Day 2 November 03, 2015 Tuesday
Hiroshi Maeda, Ph.D., MD, Sojo University, Japan
Title: Toward full understanding of the EPR effect in primary and metastatic tumor, and issues of heterogeneity: For tumor selective delivery and imaging using nano-particles
Steven LaPlante, NMX Research and Solutions, Canada
Title: Discovering Quality Drug Seeds by Practical NMR-based Fragment Screening
Dawei Li, Ph.D, Shanghai Jiao Tong University, China
Title: Monoclonal antibody targeting of tumour micro environment
Brent E. Korba, Ph.D, Georgetown University, USA
Title: Antivirals for norovirus
Daekyu Sun, Ph.D., University of Arizona, USA
Title: Small Molecules Targeting Human Oncogenes: Promising Anti Cancer Therapeutics
Simone Chevalier, McGill University Health Center, Canada
Title: Reliability of the dog prostate cancer-1 model for translational research aiming to recapitulate in canines the advanced form of prostate cancer in man
Maria Kontoyianni, Ph.D, Southern Illinois University Edwardsville, USA
Title: Predicting the Binding Partners of Novel Ligands via Computational Chemogenomics
Shang-Yi Anne Tsai, Ph.D, National Institute on Drug Abuse, NIH, USA
Title: Sigma-1 receptor: the novel therapeutic target for neurodegenerative disorders
Agnes Pottier, Ph.D, Nanobiotix, France
Title: New use of metals as nano-sized radio-enhancers
Ram Samudrala, Ph.D, State Univeristy of New York, USA
Title: Interactomics: Computational Analysis of Novel Drug Opportunities
Ye Fang, Ph.D, Corning Incorporated, USA
Title: Label-free resonant waveguide grating biosensor for drug and biology discovery
George G Chen, Ph.D, The Chinese University of Hong Kong, China
Title: Hypoxia-inducible factor-2a inhibits solid tumor growth through up-regulation of apoptosis
Ruth G. Perez, Ph.D, Texas Tech University Health Sciences Center, USA
Title: Compounds that stimulate neurotrophic factor expression may reduce alpha-synuclein pathology
Shunsaku Kimura, Kyoto University, Japan
Title: Activation and Evasion on Immune system with Using Nanocarriers of Molecular Assemblies
Qi Shi, Ph.D, HCL Technologies, USA
Title: The application of pipeline pilot (FRESH) in drug lead-optimization
Shyama D. Patel, Weill Cornell Medical College, USA
Title: Preclinical Studies in Neonatal Hypoxic Ischemic Encephalopathy: Therapeutic Hypothermia and Mast Cell Stabilization
Ian R. Catchpole, Ph.D, GlaxoSmithKline Medicines Research Centre, UK
Title: Anti-amyloid beta (Ab) mAb reduces retinal deposition of Ab & activated C3 in age-related macular degeneration mouse model.
Young Researchers
Lilian Fernandes Silva, University of Eastern Finland, Finland
Title: Central and toxicological activity of Nicandrin B - a withanolide, extracted from Datura ferox
Henrike Hoeke, University of Leipzig, Germany
Title: Assessment of maternal drug intake by bio monitoring during pregnancy until the 3rd perinatal year
Rasa Ghaffarian, University of Maryland - College Park, USA
Title: Encapsulation of ICAM-1 targeted nanocarriers into chitosan-alginate microbeads provides gastric protection and controlled release for oral drug delivery
Xiongwei Deng, Beijing University of Technology, China
Title: Nanoparticles modified with tumor-targeting MUC-1 aptamer deliver miR-34a for effective gene therapy against non-small cell lung cancer
Day 3 November 04, 2015 Wednesday
Krishnan Chakravarthy, MD, Ph.D NanoAxis, LLC., USA
Title: Developing New Nanomedicine Technologies for the Treatment of Chronic Pain
Wasana Sumanasekera, Ph.D, Sullivan University College of Pharmacy, USA
Title: Wonders of Cigarette Smoke: Hurting Heart and Serving Cancer
Jong-Young Kwak, Ph.D Ajou University, Korea
Title: Combined cancer therapy with SR-A agonist and dendritic cells
Gislei Frota Aragao, Ph.D State University of Ceara, Brazil
Title: Alterations in metabolism of brain amino acids and inhibitory effects on PKC are possibly correlated with anticonvulsant effects of the isomeric mixture of a- and b-amyrin from Protium heptaphyllum
Apurba K Bhattacharjee, Ph.D Georgetown University, USA
Title: Discovery of sub-type specific muscarinic receptor antagonists as potential alternative to atropine
Rajamma Mathew, Ph.D, New York Medical College, USA
Title: Caveolin-1 in pulmonary hypertension: a friend or a foe?
Eileen K. Jaffe, Fox Chase Cancer Center, TUHS, USA
Title: Impact of Quaternary Structure Dynamics on Drug Discovery – An Update
Fang Zhang, Beijing University of Technology, China
Title: Targeted delivery of miR-203 by self-assembly Nano-carrier suppresses esophageal cancer growth and metastasis
Paresh Gandhi, Advance Research Products LLC, USA
Title: Anti-microbial potential of novel synthetic nicotine derivatives
Kishor S. Jain, Rasiklal M. Dhariwal Institute of Pharmaceutical Education and Research (RMDIPER), India
Title: Some molecular targets for antihyperlipidemic drug research
Elsayed Ahmed Baraya, B.Sc, M.Sc, Primary health care corporation, Qatar
Title: Rational use of medicines in Qatar
Jianhai Chen, Nanfang Hospital, China
Title: The design of gene delivery systems based on PAMAM derivative as carrier and their transfection mechanism
Alexander E. Berezin, Ph.D, State Medical University, Ukraine
Title: Impaired immune phenotype of circulating endothelial-derived microparticles in none-diabetic patients with chronic heart failure: impact on insulin resistance
Hamisi M Malebo, National Institute for Medical Research, Tanzania
Title: Anti-protozoal potential of aporphine and protoberberine alkaloids from Annickia kummeriae (Engl. & Diels) Setten & Maas (Annonaceae)
Yu Cui-Yun, Ph.D, University of South China, China
Title: Fabrication of a novel PDC macromolecular pro-drug based core-shell micell
Young Researchers
Msou Soufiane, Cadi Ayyad University Marrakech, Morocco
Title: Phytochemical composition, antioxidant and antimicrobial activities of the essential oils from Fraxinus dimorpha coss & dur.
Vikas Saini, University of Delhi, India
Title: An evaluation of anticancer activity of Diallyl Disulfide analogs: an active principle of Garlic
Mai F. Tolba, The American University in Cairo, Egypt
Title: Metformin alone or combined with CAPE protects against benign prostate hypertrophy in rats: Role of ER-α/IGF-1R/Phosphoinositide 3-kinase/Akt
Session Chairs
Harold C. Smith
University of Rochester, USA
University of Rochester, USA
Ram Samudrala
State Univeristy of New York, USA
State Univeristy of New York, USA
Hiroshi Maeda
Sojo University, Japan
Sojo University, Japan
Nikolai Zhelev
Abertay University, UK
Abertay University, UK
Steven LaPlante
NMX Research and Solutions, Canada
NMX Research and Solutions, Canada
Krishnan Chakravarthy
NanoAxis, LLC., USA
NanoAxis, LLC., USA